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N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide

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N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:dCeMM2
CAS:296771-07-8
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:dCeMM2
CAS:296771-07-8
Purity:99.68% Package:5mg;43USD|10mg;73USD|25mg;158USD
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Products Intro: Product Name:dCeMM2
CAS:296771-07-8
Purity:0.98 Package:5mg，10mg，100mg，500mg，1g，5g，10g，more
Company Name: Aladdin Scientific
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Products Intro: Product Name:dCeMM2
CAS:296771-07-8
Purity:99% Package:$90.9/5mg;$150.9/10mg;$320.9/25mg;$545.9/50mg;$870.9/100mg;Bulk package Remarks:99%
Company Name: ATK CHEMICAL COMPANY LIMITED  
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Products Intro: Product Name:N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide
CAS:296771-07-8
Purity:95% Package:1G;5G;10G;50G;100G;1KG

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide manufacturers

  • dCeMM2
  • dCeMM2 pictures
  • $31.00 / 1mg
  • 2024-11-19
  • CAS:296771-07-8
  • Min. Order:
  • Purity: 99.68%
  • Supply Ability: 10g
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Basic information
Product Name:N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide
Synonyms:N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide;dCeMM2;Acetamide, N-(5-chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)-;2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(5-chloropyridin-2-yl)acetamide;dCeMM2, 10 mM in DMSO
CAS:296771-07-8
MF:C16H11ClN6OS
MW:370.81614
EINECS:
Product Categories:
Mol File:296771-07-8.mol
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Structure
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Chemical Properties
density 1.60±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble to 50 mM in DMSO
form Solid
pka10.25±0.50(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Usage And Synthesis
Biological ActivitydCeMM2 is a molecular glue degrader. Induces ubiquitination and degradation of cyclin K by eliciting an interaction of CDK12-cyclin K with a CRL4B ligase complex. dCeMM2 displays near-total degradation of protein at 2.5 μM within 2h. Cell-permeable.
storageStore at -20°C
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Preparation Products And Raw materials
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