Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:N-(NBD-AMinohexanoyl) D-erythro-Sphingosine CAS:94885-02-6 Package:10Mg,1Mg
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Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:C6-NBD-CERAMIDE CAS:94885-02-6 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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C6-NBD-CERAMIDE manufacturers
- Golgi-Tracker Green
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- $0.00 / 1mg
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2024-03-29
- CAS:94885-02-6
- Min. Order: 1mg
- Purity: >95.00%
- Supply Ability: 1mg
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| C6-NBD-CERAMIDE Basic information |
| C6-NBD-CERAMIDE Chemical Properties |
Melting point | 85-88 °C | density | 1.153±0.06 g/cm3(Predicted) | storage temp. | −20°C | solubility | Soluble in DMSO (35 mg/mL) | pka | 13.54±0.20(Predicted) | form | solid | color | Orange | Stability: | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| C6-NBD-CERAMIDE Usage And Synthesis |
Description | C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C6 ceramide in the inhibition of viral glycoprotein transport through the Golgi. C6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane. | Chemical Properties | Rust or Dark Yellow Solid | Uses | A vital fluoresent stain for the Golgi apparatus. | Definition | ChEBI: N-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}sphingosine is an N-acylsphingosine that is sphingosine with the amino nitrogen converted into a 6-{[N-(7-nitrobenzo-2,1,3-oxadiazol-4-yl)amino]}hexananamido group. It has a role as a fluorescent probe. | References | Chazotte (2012),?Labeling Golgi with Fluorescent Ceramides;?Cold Spring Harb. Protoc. (8):pdb.prot070599
van Meer et al. (1987),?Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells; J. Cell Biol.?105 1623
Don and Rosen (2008),?A fluorescent plate reader assay for ceramide kinase; Anal. Biochem.?375 265
Nikolova-Karakashian (2021),?Methods to Characterize Synthesis and Degradation of Sphingomyelin at the Plasma Membrane and Its Impact on Lipid Raft Dynamics; Methods Mol. Biol.?2187 113 |
| C6-NBD-CERAMIDE Preparation Products And Raw materials |
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