| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Monoclonal Anti-γ-Tubulin antibody produced in mouse
Purity:clone GTU-88, ascites fluid Remarks:IgG fraction of antiserum, buffered aqueous solution
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| Company Name: |
Sigma-Aldrich Japan K.K.
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| Tel: |
81-3-6756-8200 |
| Email: |
sialjp@sial.com |
| Products Intro: |
Product Name:MONOCLONAL ANTI-Β-TUBULIN ANTIBODY PRODUCED IN MOUSE
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-GAMMA-TUBULIN Basic information |
| | ANTI-GAMMA-TUBULIN Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| | ANTI-GAMMA-TUBULIN Usage And Synthesis |
| Uses | Monoclonal Anti-γ-Tubulin antibody has been used in western blotting, indirect immunofluorescence (IF) and immunofluorescence staining.
Monoclonal Anti-γ-Tubulin is also suitable for use in immunochemical applications such as immunoblotting, immunocytochemical staining of cultured cells and in ELISA. | | Uses | Monoclonal Anti-γ-Tubulin antibody produced in mouse has been used in following studies:
- Western blot analysis
- Immunohistochemistry
- Immunocytology
| | General Description | γ-Tubulin (48 kDa) is a highly conserved protein. The microtubule cytoskeleton consists of a dynamic, highly polarized network of microtubules filaments, microtubule-associated proteins, microtubule motors, and microtubule-organizing proteins. γ-Tubulin is found as part of a large protein complex containing at least five other proteins and has a shape of a ring (γ-tubulin ring complex, γ-TuRC) that is roughly the same diameter as a microtubule. | | Biochem/physiol Actions | γ-Tubulin nucleates microtubule assembly throughout the mammalian cell cycle in vivo. In Aspergillus nidulans, γ-tubulin facilitates attachment of microtubules to the spindle pole body, nuclear division and microtubule assembly. Ubiquitination of γ-tubulin by breast cancer 1 protein (BRCA1) is a crucial step in the regulation of centrosome number. Overexpression of γ-tubulin is observed in lung cancer. Tubulin γ 2 (TUBG2) plays a vital role in cell growth. Aberration in the γ-tubulin gene alters microtubule assembly. The expression levels of γ-tubulin can be considered as an important prognostic indicator for patients with astrocytomas. |
| | ANTI-GAMMA-TUBULIN Preparation Products And Raw materials |
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