OXYTHIAMINE HYDROCHLORIDE

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Company Name: Antai Fine Chemical Technology Co.,Limited
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Products Intro: Product Name:OXYTHIAMINE HYDROCHLORIDE
CAS:614-05-1
Purity:0.98 Package:1KG;5KG;25KG
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
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Products Intro: Product Name:Oxythiamine hydrochloride
CAS:614-05-1
Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:High quality
Company Name: Nextpeptide Inc
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Products Intro: Product Name:Oxythiamine · HCl
CAS:614-05-1
Purity:98% Min. Package:5KG;1KG
Company Name: GIHI CHEMICALS CO.,LIMITED
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Products Intro: Product Name:Oxythiamine hydrochloride
CAS:614-05-1
Purity:99 Package:5KG;1KG,25kg
Company Name: Aladdin Scientific
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Products Intro: Product Name:Oxythiamine chloride hydrochloride
CAS:614-05-1
Purity:>=95% Package:$36.9/1g;$111.9/5g;$406.9/25g;Bulk package Remarks:95%
OXYTHIAMINE HYDROCHLORIDE Basic information
Product Name:OXYTHIAMINE HYDROCHLORIDE
Synonyms:5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE;5-[2-HYDROXYETHYL]-3-[4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL]-4-METHYLTHIAZOLIUM CHLORIDE HYDROCHLORIDE;Oxametholone Hydrochloride;hydroxythiaminechloridehydrochloride;hyl)-4-methyl-,chloride,monohydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;OXYTHIAMINE HCL;OXYTHIAMINE HYDROCHLORIDE
CAS:614-05-1
MF:C12H17Cl2N3O2S
MW:338.25
EINECS:
Product Categories:Biochemistry;Vitamin Derivatives;Vitamins
Mol File:614-05-1.mol
OXYTHIAMINE HYDROCHLORIDE Structure
OXYTHIAMINE HYDROCHLORIDE Chemical Properties
Melting point >190°C (subl.)
storage temp. -20°C
solubility DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
WGK Germany 3
RTECS XJ7034100
MSDS Information
ProviderLanguage
SigmaAldrich English
OXYTHIAMINE HYDROCHLORIDE Usage And Synthesis
Usesthiamine antagonist
UsesOxythiamine chloride hydrochloride is suitable for use:
  • as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
  • as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
  • in the synthesis of oxythiamineH picrolonate salt

DefinitionChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.
General DescriptionOxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.
Biochem/physiol ActionsOxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.
OXYTHIAMINE HYDROCHLORIDE Preparation Products And Raw materials
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OXYTHIAMINE HYDROCHLORIDE