| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:DK419
CAS:2102672-22-8
Purity:98% HPLC Package:100mg，250mg，1g
|
| Company Name: |
Chengdu Peter-like Biotechnology Co., Ltd.
|
| Tel: |
028-81700200 18108052721 |
| Email: |
2850505130@qq.com |
| Products Intro: |
Product Name:DK419
CAS:2102672-22-8
Purity:HPLC>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:DK419
CAS:2102672-22-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
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| Product Name: | DK419 | | Synonyms: | DK419;inhibit,DK419,Wnt,β-catenin,Inhibitor,DK 419,Beta catenin,DK-419;1H-Benzimidazole-7-carboxamide, 5-chloro-2-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]- | | CAS: | 2102672-22-8 | | MF: | C16H8ClF6N3O | | MW: | 407.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2102672-22-8.mol |  |
| | DK419 Chemical Properties |
| Boiling point | 417.7±45.0 °C(Predicted) | | density | 1.611±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 83.33 mg/mL (204.39 mM) | | pka | 7.22±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | DK419 Usage And Synthesis |
| Description | DK419 is a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. DK419 inhibited Wnt/β-catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally. |
| | DK419 Preparation Products And Raw materials |
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