Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:SLM6031434 (hydrochloride) CAS:1897379-34-8 Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:SLM6031434 hydrochloride CAS:1897379-34-8 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
Zhengzhou convergence chemical co., LTD
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Tel: |
0371-0371-55153829 18003835034 |
Email: |
2853979819@qq.com |
Products Intro: |
Product Name:(S)-2-(3-(4-(Octyloxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide hydrochloride CAS:1897379-34-8 Purity:98% Package:100mg 250mg 500mg 1g 2g 5g 10g 25g 50g 100g 250g 500g 1kg
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| (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride Basic information |
| (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 5 mg/ml | form | A crystalline solid |
| (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride Usage And Synthesis |
Uses | SLM 6031434 Hydrochloride is a Sphk2 inhibitor (Ki = 0.4 μM for mouse Sphk2). Exhibts some selectivity for Sphk2 over Sphk1 (Ki > 20 μM). Decreases levels of sphingosine-1-phosphate (S1P) in U937 cells in vitro and increases blood levels of S1P in wild-type mice. | storage | Store at -20°C |
| (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride Preparation Products And Raw materials |
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