Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:1(S),9(R)-()-Bicuculline methbromide CAS:66016-70-4 Purity:>= 98 % HPLC, solid Package:25mg, 125mg Remarks:B7561
|
Company Name: |
TargetMol Chemicals Inc.
|
Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:Bicuculline methobromide CAS:66016-70-4 Package:10mg
|
Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
Tel: |
0513-66337626 18051384581 |
Email: |
sales@chemhifuture.com |
Products Intro: |
Product Name:1(S),9(R)-()-Bicuculline methbromide CAS:66016-70-4 Purity:98%+ HPLC Package:10mg,500mg,1g,2g,5g,10g,More
|
Company Name: |
Riedel-de Haen AG
|
Tel: |
800 558-9160 |
Email: |
|
Products Intro: |
Product Name:1(S),9(R)-()-Bicuculline methbromide CAS:66016-70-4
|
|
| (-)-BICUCULLINE METHBROMIDE Basic information |
Product Name: | (-)-BICUCULLINE METHBROMIDE | Synonyms: | (5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1);1(S),9(R)-(-)-Bicuculline methbromide;(-)-BICUCULLINE METHBROMIDE;[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide;1(s),9(r)-(-)-bicuculline methobromide;(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;d-Bicuculline methobromide;(+)-Bicuculline methobromide|||d-Bicuculline methobromide|||(+)-Bicuculline methobromide | CAS: | 66016-70-4 | MF: | C21H20NO6.Br | MW: | 462.294 | EINECS: | | Product Categories: | | Mol File: | 66016-70-4.mol | |
| (-)-BICUCULLINE METHBROMIDE Chemical Properties |
storage temp. | 2-8°C | solubility | aqueous base: unstable | form | solid | color | white | Water Solubility | Soluble to 50 mM in water |
| (-)-BICUCULLINE METHBROMIDE Usage And Synthesis |
Uses | 1(S),9(R)-(-)-Bicuculline methbromide has been used:
- as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culture
- in artificial cerebrospinal fluid (ACSF) formature dentate granule neurons
- in hypothalamic explant cultures
| Biochem/physiol Actions | 1(S),9(R)-(?)-Bicuculline methbromide is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels. It is the water-soluble derivative of (+)-bicuculline. | storage | Store at RT |
| (-)-BICUCULLINE METHBROMIDE Preparation Products And Raw materials |
|