- BN82002
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- $38.00 / 1mg
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2024-11-19
- CAS:396073-89-5
- Min. Order:
- Purity: 99.91%
- Supply Ability: 10g
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| | BN82002 HYDROCHLORIDE SALT Basic information |
| Product Name: | BN82002 HYDROCHLORIDE SALT | | Synonyms: | BN82002 hydrochloride;CDC25 Phosphatase Inhibitor I, BN82002;BN 82002;BN-82002;CDC25 Phosphatase Inhibitor I, BN82002 - CAS 396073-89-5 - Calbiochem;CDC25 Phosphatase Inhibitor I;Phenol, 4-(dimethylamino)-2-methoxy-6-[[methyl[2-(4-nitrophenyl)ethyl]amino]methyl]-;CDC25C,BN82002,CDC25A,BN-82002,inhibit,CDC25B3,MIA PaCa-2,Inhibitor,CDC25B2,BN 82002,Phosphatase;BN82002, 10 mM in DMSO | | CAS: | 396073-89-5 | | MF: | C19H25N3O4 | | MW: | 359.42 | | EINECS: | | | Product Categories: | | | Mol File: | 396073-89-5.mol |  |
| | BN82002 HYDROCHLORIDE SALT Chemical Properties |
| Melting point | 92-93 °C | | Boiling point | 532.6±50.0 °C(Predicted) | | density | 1.216±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 10 mg/mL | | form | solid | | pka | 10.07±0.48(Predicted) | | color | tan |
| | BN82002 HYDROCHLORIDE SALT Usage And Synthesis |
| Uses | BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. BN82002 displays ~20-fold greater selectivity over CD45 tyrosine phosphatase[1]. | | Biological Activity | Cell permeable: yes', 'Primary Target
CDC25A', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 2.4, 3.9, 6.3, 5.4, and 4.6 μM for CDC25 phosphatase family 25A, 25B2, 25B3, 25C, and 25C-cat, respectively | | References | [1] Brezak MC, et al. A novel synthetic inhibitor of CDC25 phosphatases: BN82002. Cancer Res. 2004 May 1;64(9):3320-5. DOI:10.1158/0008-5472.can-03-3984 |
| | BN82002 HYDROCHLORIDE SALT Preparation Products And Raw materials |
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