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N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:300670-16-0
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Shanghai Chaolan Chemical Technology Center  
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Products Intro: CAS:300670-16-0
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:C2-8
CAS:300670-16-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:C2-8
CAS:300670-16-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: Energy Chemical  
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Products Intro: Product Name:N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid
CAS:300670-16-0
Purity:NULL Package:25mg;5mg Remarks:NULL
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Basic information
Product Name:N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
Synonyms:N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI;Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl);Polyglutamine Aggregation Inhibitor III, C2-8;C2-8 (polyQ aggregation inhibitor C2-8);N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid
CAS:300670-16-0
MF:C19H14Br2N2O3S
MW:510.2
EINECS:
Product Categories:
Mol File:300670-16-0.mol
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Structure
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Chemical Properties
density 1.760±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ~20 mg/mL
pka7.49±0.10(Predicted)
form solid
color off-white
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
WGK Germany 3
MSDS Information
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Usage And Synthesis
DescriptionC2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington''s disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntington''s disease.
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Preparation Products And Raw materials
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