Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 基本信息
| 中文名称 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- |
|---|---|
| 中文同义词 | 哌柏西利杂质CHPP;帕博西尼杂质C;哌柏西利羟胺衍生物杂质;帕布昔利布22;6-乙酰基-8-环戊基-2-((5-(4-羟基哌嗪-1-基)吡啶-2-基)氨基)-5-甲基吡啶[2,3-D]嘧啶-7(8H)-酮(帕布昔利布杂质);帕布昔利布(帕博西尼)杂质92;哌柏西利杂质J |
| 英文名称 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- |
| 英文同义词 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl-;6-acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one;N-Hydroxy Palbociclib;6-Acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity) |
| CAS号 | 2231085-26-8 |
| 分子式 | C24H29N7O3 |
| 分子量 | 463.53 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2231085-26-8.mol |
| 结构式 | ![Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 结构式](CAS/20200119/GIF/2231085-26-8.gif) |
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 性质
| 熔点 | >200°C (dec.) |
|---|---|
| 沸点 | 742.2±70.0 °C(Predicted) |
| 密度 | 1.393±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于DMSO（少许）、甲醇（少许） |
| 酸度系数(pKa) | 12.88±0.20(Predicted) |
| 形态 | 固体 |
| 颜色 | 浅黄色至厚黄色 |