Company Name: |
cjbscvictory
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Tel: |
13348960310 13348960310 |
Email: |
3003867561@qq.com |
Products Intro: |
Product Name:JAK-IN-3 CAS:1400876-94-9 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:JAK-IN-3;JAKIN3,JAK IN 3 CAS:1400876-94-9 Purity:98% Package:10 mg;25 mg
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| JAK-IN-3 Basic information |
Product Name: | JAK-IN-3 | Synonyms: | JAK-IN-3 (COMPOUND 22);JAK-IN-3;JAKIN3,JAK IN 3;Pyrrolo[1,2-b]pyridazine-3-carboxamide, 4-[[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-6-phenyl- | CAS: | 1400876-94-9 | MF: | C18H20N4O3 | MW: | 340.38 | EINECS: | | Product Categories: | | Mol File: | 1400876-94-9.mol | ![JAK-IN-3 Structure](CAS/20210305/GIF/1400876-94-9.gif) |
| JAK-IN-3 Chemical Properties |
density | 1.39±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 12.70±0.50(Predicted) | form | Solid | color | Light brown to brown |
| JAK-IN-3 Usage And Synthesis |
Biological Activity | JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1]. | References | [1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311. |
| JAK-IN-3 Preparation Products And Raw materials |
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