7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Suppliers list
Company Name: Shanghai meikai technology co., ltd  
Tel: 021-18721550-091 18721550091
Email: yangdong@pharma.com
Products Intro: Product Name:7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one
CAS:2056122-65-5
Purity:>95% Package:10 mg|25 mg| Remarks:MC012559
7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Basic information
Product Name:7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one
Synonyms:7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one;Thieno[3,2-b]pyridin-5(4H)-one, 7-amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
CAS:2056122-65-5
MF:C19H20N6OS
MW:380.47
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Mol File:2056122-65-5.mol
7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Structure
7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Chemical Properties
density 1.418±0.06 g/cm3(Predicted)
pka10.67±0.10(Predicted)
Safety Information
MSDS Information
7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Usage And Synthesis
Uses7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one is a HPK1 kinase inhibitor and has been shown to have in vivo antitumor activity. HPK1 kinase has been identified as a novel drug target for antitumor immunotherapy, as this kinase is involved in the extracellular-signaling pathways that inhibit the T-cell immuno antitumor response.
7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Preparation Products And Raw materials
Tag:7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one(2056122-65-5) Related Product Information