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| | Methoxamine Basic information |
| Product Name: | Methoxamine | | Synonyms: | METHOXAMINE;AURORA KA-7725;2-AMINO-1-(2,5-DIMETHOXYPHENYL)-1-PROPANOL | | CAS: | | | MF: | C11H17NO3 | | MW: | 211.26 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | Methoxamine Chemical Properties |
| pka | pKa 9.32(H2O,t =25±0.5,I=0.01)(Approximate) |
| | Methoxamine Usage And Synthesis |
| General Description | Methoxamine is another 1-agonist and parenteralvasopressor used therapeutically and so have fewcardiac stimulatory properties. It is bioactivated byO-demethylation to an active m-phenolic metabolite. In fact,it tends to slow the ventricular rate because of activation ofthe carotid sinus reflex. It is less potent than phenylephrineas a vasoconstrictor. Methoxamine is used primarily duringsurgery to maintain adequate arterial blood pressure, especiallyin conjunction with spinal anesthesia. It does not stimulatethe CNS. Because it is not a substrate for COMT, itsDOA is significantly longer than NE. |
| | Methoxamine Preparation Products And Raw materials |
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