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| Product Name: | MS1943 | | Synonyms: | MS1943;1,6-Dimethyl-2-aminomethyl-3-benzyloxypyridin-4(1H)-one;1H-Indazole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-;6-(6-(4-(2-(2-(Adamantan-1-yl)acetamido)ethyl)piperazin-1-yl)pyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide;MS 1943,degrader,Histone Methyltransferase,breast,Apoptosis,inhibit,triple-negative,proliferation,methyltransferase,MS1943,cancer,Inhibitor,cytotoxic,MS-1943,TNBC | | CAS: | 2225938-17-8 | | MF: | C42H54N8O3 | | MW: | 718.93 | | EINECS: | | | Product Categories: | | | Mol File: | 2225938-17-8.mol |  |
| | MS1943 Chemical Properties |
| density | 1.36±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO:100.0(Max Conc. mg/mL);139.1(Max Conc. mM) | | form | A solid | | pka | 12.56±0.46(Predicted) | | color | Light yellow to yellow |
| | MS1943 Usage And Synthesis |
| Uses | MS1943 is used in the preparation of heterocyclic compounds as EZH2 ligands and their compositions and methods for treating EZH2-mediated cancer. MS1943 itself significantly reduces EZH2 protein levels in numerous triple-negative breast cancer |
| | MS1943 Preparation Products And Raw materials |
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