H-7 DIHYDROCHLORIDE

H-7 DIHYDROCHLORIDE Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:H-7 dihydrochloride CAS:108930-17-2 Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Career Henan Chemica Co
Tel:	+86-0371-86658258 15093356674;
Email:	laboratory@coreychem.com
Products Intro:	Product Name:H-7 DIHYDROCHLORIDE CAS:108930-17-2 Purity:95%~99.99% heidi@coreychem.com Package:1KG;2.8USD

Company Name:	Wuhan Topule Biopharmaceutical Co., Ltd
Tel:	+8618327326525
Email:	masar@topule.com
Products Intro:	Product Name:H-7 DIHYDROCHLORIDE CAS:108930-17-2 Purity:0.98 Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Company Name:	Aladdin Scientific
Tel:	+1-+1(833)-552-7181
Email:	sales@aladdinsci.com
Products Intro:	Product Name:Protein kinase inhibitor H-7 dihydrochloride CAS:108930-17-2 Purity:>=98% Package:$157.9/10mg;$345.9/25mg;$543.9/50mg;$939.9/100mg;Bulk package Remarks:98%

Company Name:	Mainchem Co., Ltd.
Tel:	+86-0592-6210733
Email:	sale@mainchem.com
Products Intro:	Product Name:H-7 DIHYDROCHLORIDE CAS:108930-17-2

H-7 DIHYDROCHLORIDE Basic information

Product Name:	H-7 DIHYDROCHLORIDE
Synonyms:	H-7 DIHYDROCHLORIDE;H-7;(+/-)-1-(5-ISOQUINOLINESULPHONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE;1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE;(+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL;1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL;(-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, DI-HCL SALT;(+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE
CAS:	108930-17-2
MF:	C14H19Cl2N3O2S
MW:	364.29
EINECS:
Product Categories:	Protein Kinase Inhibitors and Activators
Mol File:	108930-17-2.mol

H-7 DIHYDROCHLORIDE Chemical Properties

Melting point	215-225 °C
storage temp.	2-8°C
solubility	H₂O: 20 mg/mL
form	Light yellow lyophilized solid
color	White to Off-White
BRN	5840763
CAS DataBase Reference	108930-17-2(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

H-7 DIHYDROCHLORIDE Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases
Uses	H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.
Definition	ChEBI: A hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride.
General Description	A broad-based, cell-permeable, reversible, ATP-competitive serine-threonine kinase inhibitor. Potent inhibitor of myosin light chain kinase (K_i = 97 μM), protein kinase A (K_i = 3.0 μM), protein kinase C (K_i = 6 μM), and protein kinase G (K_i = 5.8 μM). Induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells. Also inhibits telomerase activity in quercetin-, H-89-, or herbimycin A-treated NPC-076 cells.
Biochem/physiol Actions	Target Ki: 3.0 μM, 97 μM, 6.0 μM, 5.8 μM against protein kinase A , myosin light chain kinase, protein kinase C , and protein kinase G, respectively
storage	Store at RT

H-7 DIHYDROCHLORIDE Preparation Products And Raw materials

Tag:H-7 DIHYDROCHLORIDE(108930-17-2) Related Product Information

1-METHANESULFONYL-PIPERAZINE 2-Methylpiperazine PIPERAZINE DIHYDROCHLORIDE 1-BENZENESULFONYL-PIPERAZINE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE 1,4-BIS[3-(3,4,5-TRIMETHOXYBENZOYLOXY)PROPYL]HOMOPIPERAZINE DIHYDROCHLORIDE 1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE 1-(3-TRIFLUOROMETHYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE 1,4-BUTANEDIAMINE DIHYDROCHLORIDE 1-(3-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE 1,3-PROPANEDIAMINE DIHYDROCHLORIDE 1,4'-BIPIPERIDINE DIHYDROCHLORIDE,[1,4']BIPIPERIDINYL DIHYDROCHLORIDE 1,4-BENZENEDIAMINE DIHYDROCHLORIDE [1,4']BIPIPERIDINYL DIHYDROCHLORIDE 10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE,1-(3-Methylphenyl)piperazine dihydrochloride 1-(4-Bromophenyl)piperazine 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

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