| Company Name: |
Ontores Biotech
|
| Tel: |
0571-88760729 18072970094 |
| Email: |
supports@ontorespeptide.com |
| Products Intro: |
Product Name:ER
Purity:98% Package:5mg;10mg;100mg;500mg;1KG;10KG;50KG
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| Company Name: |
zsbio
|
| Tel: |
400-810-9781 |
| Email: |
zsbio@qq.com |
| Products Intro: |
Product Name:ER
|
|
| | ANTI-ESTROGEN RECEPTOR Basic information |
| Product Name: | ANTI-ESTROGEN RECEPTOR | | Synonyms: | ANTI-HUMAN ESTROGEN RECEPTOR;ANTI-HUMAN ER;ANTI-ER;ANTI-ER (AB-1), HUMAN;ANTI-ER (AB-1) MOUSE MAB;ANTI-ESTROGEN RECEPTOR (AB-1);ANTI-ESTROGEN RECEPTOR (AB-1), HUMAN;ANTI-ESTROGEN RECEPTOR (AB-1) HUMAN (MOUSE) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-ESTROGEN RECEPTOR Structure]() |
| | ANTI-ESTROGEN RECEPTOR Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| | ANTI-ESTROGEN RECEPTOR Usage And Synthesis |
| Uses | Rabbit Anti-ESR2 antibody can be used for western blot applications at a dilution of 1μg/ml. | | General Description | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5′ UTRs and use different promoters. (provided by RefSeq) | | Biological Activity | ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers th at interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
| | ANTI-ESTROGEN RECEPTOR Preparation Products And Raw materials |
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