Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:AZ12441970 CAS:929551-91-7 Package:25mg/RMB 19400;100mg/RMB 33500;50mg/RMB 25800
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| Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Basic information |
| Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Chemical Properties |
density | 1.184±0.06 g/cm3(Predicted) | pka | 10.25±0.20(Predicted) |
| Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Usage And Synthesis |
Description | AZ12441970 is a potent toll-like receptor 7 agonist (TLR7 agonist). AZ12441970 showed efficacy in a mouse allergic airway model with minimal induction of systemic IFN-α, consistent with the low plasma levels of compound. AZ12441970 induced high levels of the notch ligands Dll1 and Dll4 mRNA, whereas immobilized DLL4 resulted in the suppression of IL-5 production. |
| Benzeneacetic acid, 3-[[[3-(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)propyl][3-(dimethylamino)propyl]amino]methyl]-, methyl ester Preparation Products And Raw materials |
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