6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride manufacturers
- Etifoxine Hydrochloride
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- $15.00 / 1KG
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2021-07-02
- CAS:56776-32-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Basic information |
| 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Chemical Properties |
Melting point | ND | storage temp. | -20°C | solubility | DMSO: ≥5mg/mL | form | powder | color | white to beige | Stability: | Hygroscopic |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 |
| 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Usage And Synthesis |
Chemical Properties | Low Melting White Solid | Uses | Psychotropic agent with anxiolytic and anticonvulsant activity. | Uses | Etifoxine hydrochloride has been used as a γ-aminobutyric acid (GABA)-receptor agonist to study its effects on insulin expression in α cell line (αTC1) | Biochem/physiol Actions | Etifoxine is an anxiolytic anticonvulsant, which promotes axonal regeneration. It binds to β2 and β3 subunits of the GABAA receptor complex, a different target site to benzodiazepines, and binds to the translocator protein (18 kDa) TSPO, formerly known as the peripheral or mitochondrial benzodiazepine receptor. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. Whereas, its anxiolytic effects involve GABAA receptors and TSPO, etifoxine′s neuroregenerative effects mainly involve TSPO. | storage | Store at +4°C |
| 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Preparation Products And Raw materials |
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