| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:(2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
CAS:2365478-58-4
Purity:95% Package:1mg;5mg;10mg Remarks:BD01369061
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| | INDEX NAME NOT YET ASSIGNED Basic information |
| Product Name: | INDEX NAME NOT YET ASSIGNED | | Synonyms: | HaloPROTAC-E;(2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide | | CAS: | 2365478-58-4 | | MF: | C39H56ClN5O8S | | MW: | 790.41 | | EINECS: | | | Product Categories: | | | Mol File: | 2365478-58-4.mol |  |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| Boiling point | 983.9±65.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | pka | 12.28±0.20(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Description | HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded. |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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