BDNF (Brain-derived Neurotrophin factor)

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BDNF (Brain-derived Neurotrophin factor) Basic information
Product Name:BDNF (Brain-derived Neurotrophin factor)
Synonyms:BDNF (Brain-derived Neurotrophin factor);polypeptide;Monoclonal Anti-FCER1A antibody produced in mouse;Anti-FCER1A, (N-terminal) antibody produced in rabbit;Anti-FcERI;Anti-Fc fragment of IgE, high affinity I, receptor for;Anti-FCE1A
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MW:0
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Mol File:Mol File
BDNF (Brain-derived Neurotrophin factor) Structure
BDNF (Brain-derived Neurotrophin factor) Chemical Properties
storage temp. -20°C
form buffered aqueous solution
Safety Information
MSDS Information
BDNF (Brain-derived Neurotrophin factor) Usage And Synthesis
General DescriptionThe IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM
Biochem/physiol ActionsThe IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.
BDNF (Brain-derived Neurotrophin factor) Preparation Products And Raw materials
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