| Company Name: |
Shanghai Taopu Industrial Co., LTD
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| Tel: |
159-00573766 18018507602 |
| Email: |
394643792@qq.com |
| Products Intro: |
Product Name:DiI
CAS:1429061-80-2
Purity:>=98% Package:标准包装10mg，20mg，50mg；1G可根据客户需求包装、定制、可以满足克级以上大量需求
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| | Phosphonium, [10-oxo-10-[4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy]decyl]triphenyl-, bromide (1:1) Basic information |
| | Phosphonium, [10-oxo-10-[4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy]decyl]triphenyl-, bromide (1:1) Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: 2mg/mL, clear | | form | Solid | | color | Orange to red |
| | Phosphonium, [10-oxo-10-[4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy]decyl]triphenyl-, bromide (1:1) Usage And Synthesis |
| Biological Activity | AP39 is a anethole dithiolethione (ADT-OH)-derivatized hydrogen sulfide (H2S) donor with a lipophilic & positively charged triphenylphosphonium (TP) moiety for mitochondrially targeted H2S release. AP39 stimulates mitochondrial electron transport and cellular bioenergetic function, protecting against mitochondrial DNA damage and cell death upon oxidative stress induction (effective conc. 30–100 nM; bEnd.3 cells). AP39 in vivo efficacy (0.1-1 μmol/kg i.v.; 0.1-0.3 mg/kg i.p.) is demonstrated in varous rodent models, including neurological damage post cardiac arrest, renal injury post ischemia-reperfusion, burn-caused organ damage, as well as brain atrophy in APP/PS1 mice. |
| | Phosphonium, [10-oxo-10-[4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy]decyl]triphenyl-, bromide (1:1) Preparation Products And Raw materials |
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