AMUSTALINE DIHYDROCHLORIDE
| 中文名称 | AMUSTALINE DIHYDROCHLORIDE |
|---|---|
| 中文同义词 | |
| 英文名称 | Amustaline Dihydrochloride |
| 英文同义词 | Amustaline Dihydrochloride;Amustaline;S-303 dihydrochloride |
| CAS号 | 210584-54-6 |
| 分子式 | C22H26Cl3N3O2 |
| 分子量 | 470.82 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 210584-54-6.mol |
| 结构式 |  |
AMUSTALINE DIHYDROCHLORIDE 性质
S‐303 (200 μM; 20 h) and glutathione (GSH; 20 mM) inactivates high titres of Chikungunya virus (CHIKV) in red blood cells (RBCs).
S-303 (200 μM; 20 h) and GSH (2 mM) inactivates >6.5 logs of HIV, >5.7 logs of Bluetongue virus, >7.0 logs of
Yersinia enterocolitica
, 4.2 logs of
Serratia marcescens
, and 7.5 logs of
Staphylococcus epidermidis in whole blood experiments
.
S-303 (200 μM; 20 h) and GSH (20 mM) inactivates approximately 5 logs or greater of
Y. enterocolitica
,
E. coli
,
S. marcescens
,
S. aureus
, HIV, bovine viral diarrhoea virus, bluetongue virus and human adenovirus 5 in RBC.
S-303 (200 μM; 20 h) retains in vitro parameters of RBC function and physiology (including total ATP, extracellular potassium, hemolysis, glucose consumption, lactate production, and pH at 37 °C) compared to conventional RBC.
S‐303 RBCs (a single transfusion) is well tolerated in rats (50 μmol/kg) and dogs (70 μmol/kg).
S‐303 RBCs (repeated transfusions) is well tolerated in rats (10 μmol/kg) and dogs (10 μmol/kg) with no histopathologic evidence of organ toxicity.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-106991A | AMUSTALINE DIHYDROCHLORIDE Amustaline dihydrochloride | 210584-54-6 | 5mg | 4000元 |
| 2024/04/30 | HY-106991A | AMUSTALINE DIHYDROCHLORIDE Amustaline dihydrochloride | 210584-54-6 | 10 mg | 6800元 |