Company Name: |
Changzhou Chenhong Biotechnology Co., Ltd.
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Tel: |
0519-85788828 13775037613 |
Email: |
sales@chemrenpharm.com |
Products Intro: |
Product Name:Acid Ceramidase-IN-1 CAS:2415225-30-6 Purity:99% Package:50mg;100mg;250mg;500mg;1g;5g
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Company Name: |
Bide Pharmatech Ltd.
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Tel: |
400-1647117 13681763483 |
Email: |
product02@bidepharm.com |
Products Intro: |
Product Name:N-Isobutyl-6-(1-methylpiperidin-4-yl)-2-oxobenzo[d]oxazole-3(2H)-carboxamide CAS:2415225-30-6 Purity:98% Package:1mg;5mg;10mg;25mg;50mg;100mg; Remarks:BD01441094
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Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
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Tel: |
0513-66337626 18051384581 |
Email: |
sales@chemhifuture.com |
Products Intro: |
Product Name:Acid Ceramidase-IN-1 CAS:2415225-30-6 Purity:98%+ HPLC Package:10mg,500mg,1g,2g,5g,10g,more
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Acid Ceramidase-IN-1 CAS:2415225-30-6 Purity:详情请点击官网 Package:1 mg
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| 3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Basic information |
| 3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Chemical Properties |
density | 1.186±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 13.11±0.20(Predicted) | form | Solid | color | White to yellow |
| 3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Usage And Synthesis |
Biological Activity | Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1]. | References | [1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664. |
| 3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Preparation Products And Raw materials |
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