| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:LpxC-IN-10
CAS:2413574-64-6
Purity:98% Package:25 mg；50 mg
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| | 3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Basic information |
| | 3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Chemical Properties |
| Boiling point | 717.7±70.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Solid | | pka | 8?+-.0.50(Predicted) | | color | White to off-white |
| | 3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Usage And Synthesis |
| Biological Activity | LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection[1].
LpxC-IN-10 (Compound A) shows MIC value < 1 pg/mL to E. coli and K. pneumoniae[1]. | | References | [1]. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1[P]. 2021. |
| | 3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Preparation Products And Raw materials |
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