| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 17702719238 |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:NXP-800; NXP 800 ; NXP800
CAS:1693734-80-3
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| Product Name: | NPX809 | | Synonyms: | NPX809;NXP-800;NPX800;NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814;6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]- | | CAS: | 1693734-80-3 | | MF: | C32H32FN5O4 | | MW: | 569.63 | | EINECS: | | | Product Categories: | | | Mol File: | 1693734-80-3.mol |  |
| | NPX809 Chemical Properties |
| Boiling point | 612.2±55.0 °C(Predicted) | | density | 1.347±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (175.55 mM; Need ultrasonic) | | pka | 11.46±0.70(Predicted) | | form | Solid | | color | Light yellow to green yellow |
| | NPX809 Usage And Synthesis |
| Biological Activity | NXP800 (CCT361814) is a potent heat shock factor 1 (HSF1) inhibitor. NXP800 has the potential for cancer research[1].
NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM)[1]. | | References | [1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1. |
| | NPX809 Preparation Products And Raw materials |
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