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Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]-

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Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:ZL0590
CAS:2230496-99-6
Purity:99.95% Package:1mg;41USD|5mg;98USD|10mg;148USD
Company Name: Hangzhou ChangCun Biotechnology Co., Ltd.  
Tel: 0571-; 13567100326
Email: 158848739@qq.com
Products Intro: Product Name:ZL0590
CAS:2230496-99-6
Purity:98%hplc Package:1g;5g;10g
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:ZL0590
CAS:2230496-99-6
Purity:99.95% Package:1mg/RMB 828;5mg/RMB 1650;10mg/RMB 2480
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:ZL0590
CAS:2230496-99-6
Purity:99.00% Package:1mg;5mg;10mg
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Email: market@ubiochem.com
Products Intro: Product Name:ZL0590
CAS:2230496-99-6
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g

Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- manufacturers

  • ZL0590
  • ZL0590 pictures
  • $68.00 / 1mg
  • 2024-11-19
  • CAS:2230496-99-6
  • Min. Order:
  • Purity: 99.95%
  • Supply Ability: 10g
Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Basic information
Product Name:Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]-
Synonyms:Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]-;ZL0590;non-KAc binding site,ZL0590,ZL-0590,BRD4 BD1,Inhibitor,acute airway inflammation,inhibit,Epigenetic Reader Domain,ZL 0590;ZL0590, 10 mM in DMSO
CAS:2230496-99-6
MF:C23H27F3N4O4S
MW:512.55
EINECS:
Product Categories:
Mol File:2230496-99-6.mol
Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Structure
Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Chemical Properties
density 1.411±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka13.38±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Usage And Synthesis
Biological ActivityZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities[1].
References[1]. Liu Z, et al. Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site. J Med Chem. 2022;65(3):2388-2408.
Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]- Preparation Products And Raw materials
Tag:Urea, N-[4-[[(2S)-2-(4-morpholinylmethyl)-1-pyrrolidinyl]sulfonyl]phenyl]-N'-[4-(trifluoromethyl)phenyl]-(2230496-99-6) Related Product Information