(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
中文名称 | (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid |
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中文同义词 | N6琥珀酰腺苷;琥珀酰腺苷 |
英文名称 | (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid |
英文同义词 | (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid;Succinyladenosine;N6-Succinyl Adenosine;(S)-N-(1,2-Dicarboxyethyl)adenosine;6-(1,2-DicarboxyethylaMino) -9-β-D-ribofuranosylpurine;N-(9-β-D-Ribofuranosyl-9H-purin-6-yl)-L-aspartic Acid;Succinoadenosine;N-<9-(β-ribofuranosyl)-9H-purin-6-yl>-L-aspartic acid |
CAS号 | 4542-23-8 |
分子式 | C14H17N5O8 |
分子量 | 383.31 |
EINECS号 | |
相关类别 | 核苷,核苷酸及寡核苷酸;Bases & Related Reagents;Chiral Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Nuc |
Mol文件 | 4542-23-8.mol |
结构式 |
(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 性质
熔点 | >180°C (dec.) |
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沸点 | 816.4±75.0 °C(Predicted) |
密度 | 2.02±0.1 g/cm3(Predicted) |
储存条件 | -20°C Freezer |
溶解度 | 可溶于DMSO(轻微)、甲醇(轻微、加热) |
形态 | 固体 |
酸度系数(pKa) | 3.52±0.23(Predicted) |
颜色 | 白色至类白色 |
(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 用途与合成方法
Human Endogenous Metabolite
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The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100–500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL.
Succinyladenosine (S-Ado) is a biochemical marker of adenylosuccinase deficiency - the genetic defect of purine de novo synthesis.S-Ado has been previously reported as normally undetectable in cereb rospinal fluid (CSF) of children not suffering from this defect.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/11/08 | HY-113284 | (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid Succinyladenosine | 4542-23-8 | 1mg | 3900元 |