(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid

(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid

中文名称(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
中文同义词N6琥珀酰腺苷;琥珀酰腺苷
英文名称(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
英文同义词(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid;Succinyladenosine;N6-Succinyl Adenosine;(S)-N-(1,2-Dicarboxyethyl)adenosine;6-(1,2-DicarboxyethylaMino) -9-β-D-ribofuranosylpurine;N-(9-β-D-Ribofuranosyl-9H-purin-6-yl)-L-aspartic Acid;Succinoadenosine;N-<9-(β-ribofuranosyl)-9H-purin-6-yl>-L-aspartic acid
CAS号4542-23-8
分子式C14H17N5O8
分子量383.31
EINECS号
相关类别核苷,核苷酸及寡核苷酸;Bases & Related Reagents;Chiral Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Nuc
Mol文件4542-23-8.mol
结构式(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 结构式

(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 性质

熔点>180°C (dec.)
沸点816.4±75.0 °C(Predicted)
密度2.02±0.1 g/cm3(Predicted)
储存条件-20°C Freezer
溶解度可溶于DMSO(轻微)、甲醇(轻微、加热)
形态固体
酸度系数(pKa)3.52±0.23(Predicted)
颜色白色至类白色

(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 用途与合成方法

Succinyladenosine,是胞内腺苷酸 (S-AMP) 经 5-核苷酸酶脱磷酸化的产物,是腺苷酸琥珀酸酶 (ASL) 缺乏的生化标志。

Human Endogenous Metabolite

The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100–500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL.

用途 

Succinyladenosine (S-Ado) is a biochemical marker of adenylosuccinase deficiency - the genetic defect of purine de novo synthesis.S-Ado has been previously reported as normally undetectable in cereb rospinal fluid (CSF) of children not suffering from this defect.

安全信息

MSDS信息

更新日期产品编号产品名称CAS号包装价格
2024/11/08HY-113284(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
Succinyladenosine
4542-23-81mg3900元

(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid 上下游产品信息

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