ASPERPHENAMATE manufacturers
- Asperphenamate
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- $112.00 / 1mg
-
2024-10-31
- CAS:63631-36-7
- Min. Order:
- Purity: 99.07%
- Supply Ability: 10g
- Asperphenamate
-
- $112.00 / 1mg
-
2024-10-31
- CAS:63631-36-7
- Min. Order:
- Purity: 99.07%
- Supply Ability: 10g
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| | ASPERPHENAMATE Basic information |
| Product Name: | ASPERPHENAMATE | | Synonyms: | ASPERPHENAMATE;(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester;Auranamide;N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester | | CAS: | 63631-36-7 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 63631-36-7.mol |  |
| | ASPERPHENAMATE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | color | White to off-white |
| | ASPERPHENAMATE Usage And Synthesis |
| Description | Asperphenamate is a fungal secondary metabolite originally isolated from A. flavipes. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). | | Uses | Asperphenamate is an α-glucosidase inhibitor isolated from Penicillium spathulatum. Asperphenamate exhibits anticancer properties and is used to synthesize N-Benzoyl-O-(N''-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth. | | Definition | ChEBI: Asperphenamate is a carboxylic ester resulting from the formal condensation of the carboxy group of N-benzoyl-L-phenylalanine with the hydroxy group of N-benzoyl-L-phenylalaninol. A metabolite found in several Pencillium and Aspergillus species, as well as in plants as a product of endophytic fungi. It has a role as an antineoplastic agent. It is a L-phenylalanine derivative, a member of benzamides and a carboxylic ester. It is functionally related to a N-benzoyl-L-phenylalanine and a N-benzoyl-L-phenylalaninol. |
| | ASPERPHENAMATE Preparation Products And Raw materials |
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