| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:3-(2-Pyridyldithio)propanoic Acid Hydrazide
CAS:115616-51-8
Package:50Mg,5Mg
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| Company Name: |
Chemsky（shanghai）International Co.,Ltd.
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:3-(2-Pyridyldithio)propanoic Acid Hydrazide
CAS:115616-51-8
Purity:98%
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| Company Name: |
Aikon International Limited
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| Tel: |
025-66113011 18112977050 |
| Email: |
sales01@aikonchem.com |
| Products Intro: |
Product Name:S-(2-thiopyridyl)mercaptopropionohydrazide
CAS:115616-51-8
Purity:95+% Package:1g;5g;10g
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| | S-(2-thiopyridyl)mercaptopropionohydrazide Basic information |
| | S-(2-thiopyridyl)mercaptopropionohydrazide Chemical Properties |
| Melting point | 87-90°C | | Boiling point | 463.6±41.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 12.81±0.35(Predicted) | | color | White | | Stability: | Light Sensitive |
| | S-(2-thiopyridyl)mercaptopropionohydrazide Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A fluorescent sulfhydryl active reagent. | | General Description | The PDPH is a heterobifunctional crosslinker containing sulfhydryl-reactive pyridyldithiol and carbonyl-reactive hydrazide moieties. Pyridyldithiols react with free sulfhydryls (-SH) to form disulfide bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, PDPH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Likewise, PDPH is useful as a sulfhydryl-addition reagent for glycoproteins and other carbohydrates; after reaction of the hydrazide to an oxidized carbohydrate, the pyridyldithiol group can be cleaved by a reducing agent to expose a sulfhydryl group. Yet another application for PDPH is to react the primary amine of the hydrazide moiety to a carboxyl group using the crosslinker EDC. |
| | S-(2-thiopyridyl)mercaptopropionohydrazide Preparation Products And Raw materials |
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