peptide 78

peptide 78 Suppliers list
Company Name: Nanjing Leon Biological Technology Co., Ltd.  
Tel: 17705183659
Email: sales@njleonbiotech.com
Products Intro: Product Name:Peptide 78
CAS:132116-62-2
Purity:98% HPLC Package:5mg;1G;10G;100G;1KG
Company Name: Nanjing Peptide Biotech Ltd.  
Tel: 025-025-58361106-805-805 13082558573
Email: liugang@njpeptide.com
Products Intro: Product Name:Peptide 78
CAS:132116-62-2
Purity:90%HPLC,95%HPLC,98%HPLC Package:5mg,20mg,100mg,250mg,500mg,1g
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Tel: 0571-87213919
Email: Eric@peptidego.com
Products Intro: Product Name:Peptide 78
CAS:132116-62-2
Purity:95% or 98% HPLC Package:1mg;5mg;10mg;50mg;100mg,1g or according to customer's detail requirement.
Company Name: Nanjing Meihao Pharmaceutical Technology Co., Ltd.  
Tel: meitaochem@126.com
Email: meitaochem@126.com
Products Intro: Product Name:Peptide 78
CAS:132116-62-2
Purity:99% HPLC Package:500g;1kg;5kg;25kg
Company Name: Hangzhou Sinoda Pharmaceutical Technology Co. LTD  
Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Products Intro: Product Name:Peptide 78
CAS:132116-62-2
Purity:95% or 98% HPLC Package:1mg;5mg;10mg;50mg;100mg,1g or according to customer's detail requirement.
peptide 78 Basic information
Product Name:peptide 78
Synonyms:peptide 78;L-Asparagine, L-threonyl-L-methionyl-L-arginyl-L-lysyl-L-prolyl-L-arginyl-L-serylglycyl-L-asparaginyl-L-prolyl-L-α-aspartyl-L-valyl-L-alanyl- (9CI)
CAS:132116-62-2
MF:C62H107N23O21S
MW:1542.72
EINECS:
Product Categories:
Mol File:132116-62-2.mol
peptide 78 Structure
peptide 78 Chemical Properties
storage temp. Store at -20°C
form Solid
color White to off-white
Water Solubility Water : 100 mg/mL (64.82 mM; Need ultrasonic)
Safety Information
MSDS Information
peptide 78 Usage And Synthesis
Biological ActivityPeptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA)[1]. Peptide 78, a potent PMN chemotaxin, in the conditioned medium of human pulmonary epithelial cells (A549) stimulated with TNF-α (20 ng/mL) or IL-1β (10 ng/mL). Peptide 78 is an 8.3-kD protein with 78 amino acids containing 4 cysteines positioned identically to those of IL-8 and its homologues. Peptide 78 belongs to a supergene family that includes platelet factor-4, platelet basic protein, and its cleavage products (connective tissue activating peptide-III, β-thromboglobulin, and interferon-γ-inducible protein, macrophage inflammatory protein-2α, and macrophage inflammatory protein-2β)[1]. Peptide 78 shares several properties of PMN activation similar to either NAP-2 or LL-8. Peptide 78 stimulation of PMNs results in significant chemotactic activity, release of elastase from cytochalasin-B-pretreated cells, and the induction of free, cytosolic calcium release. Peptide 78 aids in the recruitment of PMNs into inflamed joints of RA. Peptide 78 represents one of the most abundant chemokines present in RA synovial fluid.Peptide 78 in rheumatoid arthritis synovial fluids is biologically active. Peptide 78 appears to account for almost half of the RA synovial fluid PMN chemotactic activity in vitro[1].
References[1]. A E Koch, et al. Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. J Clin Invest. 1994 Sep;94(3):1012-8.
peptide 78 Preparation Products And Raw materials
Tag:peptide 78(132116-62-2) Related Product Information
ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE PEPTIDE F (BOVINE) Peptide 5 FAEPLPSEEEGESYSKEVPEMEKRYGGFMRF peptide 74 Peptide M H-GLU-ARG-MET-ARG-PRO-ARG-LYS-ARG-GLN-GLY-SER-VAL-ARG-ARG-ARG-VAL-OH