1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate manufacturers
- Adaphostin
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- $64.00 / 5mg
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2024-11-19
- CAS:241127-58-2
- Min. Order:
- Purity: 97.31%
- Supply Ability: 10g
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| 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate Basic information |
Product Name: | 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate | Synonyms: | 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate;4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoicacidtricyclo[3.3.1.13,7]dec-1-ylester;Adaphostin;5-Dihydroxybenzyl)Amino)Benzoate;1-Adamantyl 4-((2;Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, tricyclo[3.3.1.13,7]dec-1-yl ester;1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate;Apoptosis,tyrosine kinase,inhibit,Bcr-Abl,Adaphostin,chronic myelogenous leukemia,myeloid,Inhibitor,ROS,NSC-680410,p210Bcr/abl,NSC680410,CML | CAS: | 241127-58-2 | MF: | C24H27NO4 | MW: | 393.48 | EINECS: | | Product Categories: | Pharmaceuticals;Intermediates & Fine Chemicals;Inhibitors;Aromatics;Amines | Mol File: | 241127-58-2.mol | ![1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate Structure](CAS/GIF/241127-58-2.gif) |
| 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate Chemical Properties |
storage temp. | Desiccate at +4°C | solubility | DMSO: soluble20mg/mL, clear | form | powder | color | white to beige |
| 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate Usage And Synthesis |
Uses | Novel antitumor agent that induces apoptosis in tumor cells through inhibition of the tyrosine kinase BCR/ABL. | Biological Activity | p210 bcr/abl tyrosine kinase inhibitor (IC 50 = 14 μ M). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC 50 values range from 16.8 to 216.3 nM) in vitro . Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro . |
| 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate Preparation Products And Raw materials |
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