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2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE

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Company Name: United States Biological  
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Products Intro: Product Name:2-Chloro-6-methoxy-4-methylquinoline
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2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE Basic information
Product Name:2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE
Synonyms:2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE
CAS:
MF:C11H10ClNO
MW:207.66
EINECS:
Product Categories:
Mol File:Mol File
2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE Structure
2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE Chemical Properties
storage temp. Room Temperature
solubility Chloroform, Dichloromethane
form Solid
color Grey
Safety Information
Risk Statements 41
Safety Statements 26-39
MSDS Information
2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE Usage And Synthesis
Uses2-Chloro-6-methoxy-4-methylquinoline is an intermediate in the synthesis of Tafenoquine-d3 Succinate which is the labelled analog of Tatenoquine (T004760), a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Synthesis Reference(s)The Journal of Organic Chemistry, 11, p. 803, 1946 DOI: 10.1021/jo01176a024
2-CHLORO-6-METHOXY-4-METHYL-QUINOLINE Preparation Products And Raw materials
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