| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Remarks:95%, recombinant, expressed in E. coli, buffered aqueous solution, cell culture tested
|
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Email: |
|
| Products Intro: |
|
|
| | IFN-ALPHA-A/D HUMAN Basic information |
| Product Name: | IFN-ALPHA-A/D HUMAN | | Synonyms: | INTERFERON-ALPHA-A/D HUMAN;IFN-ALPHA-A/D HUMAN;IFN-αA/D;Interferon-αA/D human | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![IFN-ALPHA-A/D HUMAN Structure]() |
| | IFN-ALPHA-A/D HUMAN Chemical Properties |
| storage temp. | -70°C | | form | buffered aqueous solution | | color | colorless |
| | IFN-ALPHA-A/D HUMAN Usage And Synthesis |
| Uses | Interferon-αA/D human has been used:
- for identification of coronavirus replicase inhibitors
- in combination with ACH-806 [1-(4-pentyloxy-3-trifluoromethylphenyl)-3-(pyridine-3-carbonyl)thiourea] to study the effect on hepatitis C virus (HCV) replication
- in combination with vitamin D to check reduction in HCV protein production in cell culture
| | Biochem/physiol Actions | Interferon-αA/D (Bg/II), also known as Universal Type I Interferon, is an α interferon hybrid that crosses the species barrier. The Bg/II denotes the restriction enzyme site from which this hybrid is constructed from recombinant human interferons αA and αD. Interferon-αA/D has been proven to be active on many mammalian cells. It can substitute for human, monkey, mouse, bovine, rat, cat, dog, rabbit, sheep, goat, horse, pig or hamster type I interferon (α, β, ω and τ). Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes), and ruminant embryos (τ subtypes). This cytokine has anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. |
| | IFN-ALPHA-A/D HUMAN Preparation Products And Raw materials |
|