Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
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Products Intro: |
Remarks:95%, recombinant, expressed in E. coli, buffered aqueous solution, cell culture tested
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| IFN-ALPHA-A/D HUMAN Basic information |
Product Name: | IFN-ALPHA-A/D HUMAN | Synonyms: | INTERFERON-ALPHA-A/D HUMAN;IFN-ALPHA-A/D HUMAN;IFN-αA/D;Interferon-αA/D human | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | ![IFN-ALPHA-A/D HUMAN Structure]() |
| IFN-ALPHA-A/D HUMAN Chemical Properties |
storage temp. | -70°C | form | buffered aqueous solution | color | colorless |
| IFN-ALPHA-A/D HUMAN Usage And Synthesis |
Uses | Interferon-αA/D human has been used:
- for identification of coronavirus replicase inhibitors
- in combination with ACH-806 [1-(4-pentyloxy-3-trifluoromethylphenyl)-3-(pyridine-3-carbonyl)thiourea] to study the effect on hepatitis C virus (HCV) replication
- in combination with vitamin D to check reduction in HCV protein production in cell culture
| Biochem/physiol Actions | Interferon-αA/D (Bg/II), also known as Universal Type I Interferon, is an α interferon hybrid that crosses the species barrier. The Bg/II denotes the restriction enzyme site from which this hybrid is constructed from recombinant human interferons αA and αD. Interferon-αA/D has been proven to be active on many mammalian cells. It can substitute for human, monkey, mouse, bovine, rat, cat, dog, rabbit, sheep, goat, horse, pig or hamster type I interferon (α, β, ω and τ). Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes), and ruminant embryos (τ subtypes). This cytokine has anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. |
| IFN-ALPHA-A/D HUMAN Preparation Products And Raw materials |
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