| Company Name: |
Nanjing Peptide Biotech Ltd.
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| Tel: |
025-025-58361106-805-805 13082558573 |
| Email: |
liugang@njpeptide.com |
| Products Intro: |
Product Name:Epafipase
CAS:208576-22-1
Purity:90%HPLC,95%HPLC,98%HPLC Package:5mg,20mg,100mg,250mg,500mg,1g
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| Company Name: |
amyjetsci
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| Tel: |
027-59626688 18771149750 |
| Email: |
sales@amyjet.com |
| Products Intro: |
Product Name:PAF Acetylhydrolase
Package:100ug/
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
CAS:208576-22-1
Remarks:recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
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| | Rpaf-ah Basic information |
| Product Name: | Rpaf-ah | | Synonyms: | 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine deacetylase-(6-400)-peptide (human);Deacetylase, 1-alkyl-2-acetyllecithin (human);Epafipase;Epafipase [usan:inn];Paf acetylhydrolase;Pafase;Rpaf-ah;2-acetyl-1-alkylglycerophosphocholine esterase | | CAS: | 208576-22-1 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Rpaf-ah Structure]() |
| | Rpaf-ah Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | color | white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| | Rpaf-ah Usage And Synthesis |
| Uses | Antiallergenic;
antiasthmatic (PAF antagonist [PAF acetylhydrolasemphor.]. | | General Description | Recombinant PAF-AH is a 420 amino acid glycoprotein which migrates with an apparent molecular mass of 47-55kDa by SDS-PAGE analysis. | | Biochem/physiol Actions | Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet activating factor acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL (low density lipoprotein) particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. High levels of PAF-AH in plasma can be an indication of resistant hypertension. Polymorphism in PAF-AH gene at A379V might be linked with ischemic stroke susceptibility. |
| | Rpaf-ah Preparation Products And Raw materials |
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