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Product Name:TQS
CAS:353483-92-8
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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BOC Sciences
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Product Name:TQS
CAS:353483-92-8
Purity:≥98% by HPLC Remarks:TQS is a type II positive allosteric modulator of α7 nACh receptors (pEC50 = 5.5) with no activity at α7 receptors at concentrations up to 0.1 mM. TQS potentiates agonist-evoked responses and reduces
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MedBioPharmaceutical Technology Inc
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Product Name:TQS
CAS:353483-92-8
Purity:98% Package:10mg; 50mg Remarks:Medbio
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| Product Name: | TQS | | Synonyms: | TQS;3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide;4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide;Inhibitor,modulator,acetylcholine,Nicotinic acetylcholine receptors,nAChR,allosteric,neuroinflammatory,positive,pain,inhibit,TQS,nicotinic;3H-Cyclopenta[c]quinoline-8-sulfonamide, 3a,4,5,9b-tetrahydro-4-(1-naphthalenyl)- | | CAS: | 353483-92-8 | | MF: | C22H20N2O2S | | MW: | 376.47 | | EINECS: | | | Product Categories: | | | Mol File: | 353483-92-8.mol |  |
| Boiling point | 609.8±65.0 °C(Predicted) | | density | 1.311±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble to 50 mM in DMSO | | form | Powder | | pka | 10.21±0.40(Predicted) | | color | Off-white to light yellow |
| Uses | TQS is a positive allosteric modulator (Type II) of alpha7 nACh receptors, functional human α7 nicotinic acetylcholine receptor (nAChR) generated from Escherichia coli that opens a new avenue for producing mammalian Cys-loop receptors to facilitate structure-based rational drug design. |
| | TQS Preparation Products And Raw materials |
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