| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:FR 900098 MonosodiuM Salt
CAS:73226-73-0
Package:100Mg,10Mg
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:FR-900098 monosodium salt
CAS:73226-73-0
Purity:>=97% (NMR) Package:5MG Remarks:F8307-5MG
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:FR900098 sodium salt
CAS:73226-73-0
Purity:95% Package:1G;10G;100G Remarks:FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
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| | FR 900098 MonosodiuM Salt Basic information |
| | FR 900098 MonosodiuM Salt Chemical Properties |
| Melting point | 184-186°C | | storage temp. | -20°C | | solubility | H2O: ≥20mg/mL | | form | powder | | color | white to light brown | | Stability: | Hygroscopic |
| | FR 900098 MonosodiuM Salt Usage And Synthesis |
| Chemical Properties | Pale Brown Solid | | Uses | The antibiotics Fosmidomycin and FR900098 are members of a unique class of phosphonic acid natural products that inhibit the nonmevalonate pathway for isoprenoid biosynthesis. Both are potent antibacterial and antimalarial compounds. | | Biochem/physiol Actions | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice. |
| | FR 900098 MonosodiuM Salt Preparation Products And Raw materials |
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