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FABP4 (human) EIA Kit

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Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Email: cayman@caymanchem.com
Products Intro: Product Name:FABP4 (human) EIA Kit
Remarks:10007614
FABP4 (human) EIA Kit Basic information
Product Name:FABP4 (human) EIA Kit
Synonyms:FABP4 (human) EIA Kit
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MW:0
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FABP4 (human) EIA Kit Structure
FABP4 (human) EIA Kit Chemical Properties
Safety Information
MSDS Information
FABP4 (human) EIA Kit Usage And Synthesis
DescriptionFatty acid binding protein 4 (AFABP; adipocyte FABP; FABP4) is a 15 kDa member of the intracellular FABP family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids). AFABP is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. In mice, targeted mutations in FABP4 (gene also called: aP2) provides significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. AFABP is also expressed in macrophages where it modulates inflammatory responses and cholesterol ester accumulation. Total or macrophage-specific FABP deficiency confers dramatic protection against atherosclerosis in apoE-/- mice. These results indicate a central role for AFABP in development of metabolic diseases through its distinct actions in adipocytes and macrophages. This Enzyme Immunometric Assay (EIA) is based on a double-antibody sandwich technique. The wells of the plate supplied with the kit are coated with a goat polyclonal antibody specific of human AFABP. This antibody will bind any human AFABP introduced in the wells (sample or standard). [Bertin Catalog No. A05181]
FABP4 (human) EIA Kit Preparation Products And Raw materials
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