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| | Thalidezine Basic information |
| Product Name: | Thalidezine | | Synonyms: | Thalidezine;5-O-DeMethylhernandezine;Thalidesine;16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-20-ol, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aS)-;Thalidezine USP/EP/BP | | CAS: | 18251-36-0 | | MF: | C38H42N2O7 | | MW: | 638.75 | | EINECS: | | | Product Categories: | | | Mol File: | 18251-36-0.mol |  |
| | Thalidezine Chemical Properties |
| Melting point | 158-159℃ | | Boiling point | 735.0±60.0 °C(Predicted) | | density | 1.206±0.06 g/cm3 (20 ºC 760 Torr) | | pka | 9.71±0.20(Predicted) |
| | Thalidezine Usage And Synthesis |
| Description | A further alkaloid of the bisbenzylisoquinoline type found in Thalictrum
fendleri Engelm, this base yields colourless crystals from Me2CO and has [α]25D +
236° (CHCl3). The ultraviolet spectrum has one absorption maximum at 283 mJ.1.
The D-methyl ether is identical with Hernandezine (q.v.). The D-ethy1 ether
forms colourless crystals with m.p. 117-120° C. | | Uses | Thalidezine is an isoquinoline alkaloid used in the treatments of cancers and neurodegenerative diseases. | | References | Shamma, Shine, Dudock., Tetrahedron, 23, 2887 (1967) |
| | Thalidezine Preparation Products And Raw materials |
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