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| | FR901464 Basic information |
| Product Name: | FR901464 | | Synonyms: | FR901464;WB 2663B;PJKVJJDQXZARCA-QHYZBLTGSA-N;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]tetrahydro-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-;FR 901464|||FR-901464|||WB 2663B | | CAS: | 146478-72-0 | | MF: | C27H41NO8 | | MW: | 507.62 | | EINECS: | | | Product Categories: | | | Mol File: | 146478-72-0.mol |  |
| | FR901464 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (197.00 mM; Need ultrasonic) | | form | Solid | | color | White to off-white |
| | FR901464 Usage And Synthesis |
| Description | FR901464 is a potent anticancer moecule that lowers the mRNA levels of oncogenes and tumor suppressor genes. | | Definition | ChEBI: A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663. |
| | FR901464 Preparation Products And Raw materials |
| Raw materials | 2-Pentynoic acid, 4-(acetyloxy)-, (4S)--->2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E)-3-methyl-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)--->1,6-Dioxaspiro[2.5]octane-4,7-diol, 5-ethenyl-7-methyl-, (3R,4R,5R,7S)--->SPLICEOSTATIN A |
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