| Company Name: |
MedChemexpress LLC
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021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:LAS101057
CAS:925676-48-8
Purity:>98% Package:5800RMB/1mg
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| | LAS101057 Basic information |
| Product Name: | LAS101057 | | Synonyms: | LAS101057;N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide;N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide(WXFC0500);Cyclopropanecarboxamide, N-[5-(3-fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]-;LAS-101057,LAS101057 | | CAS: | 925676-48-8 | | MF: | C18H14FN5O | | MW: | 335.34 | | EINECS: | | | Product Categories: | | | Mol File: | 925676-48-8.mol |  |
| | LAS101057 Chemical Properties |
| Boiling point | 509.2±50.0 °C(Predicted) | | density | 1.400±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO:125.0(Max Conc. mg/mL);372.75(Max Conc. mM) | | form | A solid | | pka | 11.70±0.20(Predicted) | | color | White to off-white |
| | LAS101057 Usage And Synthesis |
| Uses | LAS 101057 is a potent, selective, and orally efficacious A2B receptor antagonist, was identified as a clinical development candidate. It inhibits agonist-induced IL-6 production in human fibroblasts and is active in an ovalbumin (OVA)-sensitized mouse model after oral administration, reducing airway hyperresponsiveness to methacholine, Th2 cytokine production and OVA-specific IgE levels. |
| | LAS101057 Preparation Products And Raw materials |
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