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11107B

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11107B Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Pladienolide B
CAS:445493-23-2
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:Pladienolide B
CAS:445493-23-2
Purity:>=95%(HPLC) Package:$1275.9/500μg;Bulk package Remarks:95%(HPLC)
Company Name: AdooQ Bioscience CHINA  Gold
Tel: 025-58849295 18951903616;
Email: info@adooq.cn
Products Intro: Product Name:Pladienolide B
CAS:445493-23-2
Purity:99% Package:1mg
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Products Intro: Product Name:Pladienolide B
CAS:445493-23-2
Purity:98% Package:1g;10g;100g
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:Pladienolide B
CAS:445493-23-2
Purity:95% Package:100μg;500μg
11107B Basic information
Product Name:11107B
Synonyms:11107AD;11107B;PLADIENOLIDE B;SDOUORKJIJYJNW-VGQSKDSZSA-N;(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one;Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-
CAS:445493-23-2
MF:C30H48O8
MW:536.7
EINECS:
Product Categories:
Mol File:445493-23-2.mol
11107B Structure
11107B Chemical Properties
Boiling point 673.8±55.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A clear film
pka13.98±0.70(Predicted)
color Colorless to off-white
Safety Information
MSDS Information
11107B Usage And Synthesis
UsesPladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome.
UsesPladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.
storageStore at -20°C
11107B Preparation Products And Raw materials
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