| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:CRT0066101
CAS:956123-34-5
Purity:>=98% (HPLC) Package:5mg Remarks:SML1507
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:CRT0066101
CAS:956123-34-5
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:CRT 0066101
CAS:956123-34-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | CRT-0066101 Basic information |
| Product Name: | CRT-0066101 | | Synonyms: | CRT 0066101;CRT0066101;CRT-0066101;SCJXQZZYGYLKJG-CQSZACIVSA-N;6-6-(2R)-2-Aminobutylamino-1H-pyrimidin-2-ylidene-4-(1-methylpyrazol-4-yl)cyclohexa-2,4-dien-1-one,hydrochloride;Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)- | | CAS: | 956123-34-5 | | MF: | C18H22N6O | | MW: | 338.41 | | EINECS: | | | Product Categories: | | | Mol File: | 956123-34-5.mol |  |
| | CRT-0066101 Chemical Properties |
| Boiling point | 518.5±50.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | powder | | pka | 8.10±0.50(Predicted) | | color | white to beige |
| | CRT-0066101 Usage And Synthesis |
| Biochem/physiol Actions | CRT0066101 is a very potent inhibitor of Protein Kinase D (PKD) isoforms with IC50 values for PKD-1, -2 and -3 = 1, 2.5 and 2 nM, respecitively. CRT0066101 has been shown to have anticancer activity. CRT0066101 potently inhibits proliferation of PANC-1 pancreatic cells, and blocks migration and invasion of U87MG glioblastoma cells. CRT0066101 has also been shown to decrease growth of primary tumors and metastasis of ER(-) breast cancers. |
| | CRT-0066101 Preparation Products And Raw materials |
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