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| | PSI-7976 Basic information |
| Product Name: | PSI-7976 | | Synonyms: | PSI-7976;N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;Sofosbuvir (R)-Phosphate;(S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate;Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is
Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of
Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of
Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of
Sofosbuvir L-alanitate (Mixture of Diasteriomers);SFB-L-Alaninate-Model;Sofosbuvir phosphate salt;Sofosbuvir impurity 14/
RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate | | CAS: | 1190308-01-0 | | MF: | C22H29FN3O9P | | MW: | 529.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1190308-01-0.mol |  |
| | PSI-7976 Chemical Properties |
| Melting point | 76-82°C | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) | | pka | 9.39±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | PSI-7976 Usage And Synthesis |
| Uses | Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| | PSI-7976 Preparation Products And Raw materials |
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