- Optovin
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- $15.00 / 1KG
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2021-07-13
- CAS:348575-88-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Optovin
-
- $15.00 / 1KG
-
2021-07-10
- CAS:348575-88-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Optovin Basic information |
| Product Name: | Optovin | | Synonyms: | Optovin;5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone;Oprovin;4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-;CS-1131;5-((2,5-Dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one;Optovin (mixture of isomers) | | CAS: | 348575-88-2 | | MF: | C15H13N3OS2 | | MW: | 315.41 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 348575-88-2.mol |  |
| | Optovin Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Soluble in DMSO (up to 30 mg/ml) | | form | solid | | pka | 7.65±0.50(Predicted) | | color | Tan | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| | Optovin Usage And Synthesis |
| Description | Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50?= 2 μM) and mice,?in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1 | | Uses | Optovin activates human TRPA1 via structure-dependent photochemistry. | | Definition | ChEBI: Optovin is a member of the class of thiazolidinone that is rhodanine in which the two methylene hydrogens have been replaced by a 2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene group. A TRPA1 ligand that can be reversibly photoactivated. It has a role as a TRPA1 channel agonist. It is a member of pyrroles, a member of pyridines, an olefinic compound and a thiazolidinone. It is functionally related to a rhodanine. | | storage | Store at +4°C | | References | 1) Kokel?et al. (2013),?Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol.,?9?257 |
| | Optovin Preparation Products And Raw materials |
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