| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:20:0(2S-OH) Ceramide
CAS:1246298-48-5
Purity:N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine, powder Package:5MG Remarks:860820P-5MG
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| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
CAS:1246298-48-5
Purity:>99% Package:1MG;2.5MG;5MG;10MG;25MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
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| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
CAS:1246298-48-5
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Basic information |
| Product Name: | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine | | Synonyms: | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;20:0(2S-OH) Ceramide;N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine | | CAS: | 1246298-48-5 | | MF: | C38H75NO4 | | MW: | 610.01 | | EINECS: | | | Product Categories: | | | Mol File: | 1246298-48-5.mol |  |
| | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Chemical Properties |
| Boiling point | 739.3±60.0 °C(Predicted) | | density | 0.939±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 13.26±0.20(Predicted) |
| | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Usage And Synthesis |
| General Description | Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration. | | Biochem/physiol Actions | Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity. |
| | N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Preparation Products And Raw materials |
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