|
| 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid Basic information |
Product Name: | 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid | Synonyms: | 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid;ZL006;ZL 006;ZL006;Benzoic acid, 4-[[(3,5-dichloro-2-hydroxyphenyl)methyl]amino]-2-hydroxy-;iGluR,Ionotropic glutamate receptors,ZL006,ZL-006,Inhibitor,inhibit,ZL 006 | CAS: | 1181226-02-7 | MF: | C14H11Cl2NO4 | MW: | 328.15 | EINECS: | | Product Categories: | | Mol File: | 1181226-02-7.mol | ![4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid Structure](CAS/20180702/GIF/1181226-02-7.gif) |
| 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid Chemical Properties |
Boiling point | 530.4±50.0 °C(Predicted) | density | 1.617±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | DMSO: ≥5mg/mL (warmed to 60° C) | pka | 3.40±0.10(Predicted) | form | powder | color | white to tan |
Hazard Codes | Xn,N | Risk Statements | 22-50 | Safety Statements | 61 | WGK Germany | 3 |
| 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid Usage And Synthesis |
Biochem/physiol Actions | ZL006 inhibits the ischemia-induced interaction of nNOS with postsynaptic density protein-95 (PSD-95), preventing glutamate-induced excitotoxicity and cerebral ischemic damage. It does not inhibit nNOS itself. ZL006 is brain penetrant, and has been tested in both rat and mouse models of stroke. |
| 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid Preparation Products And Raw materials |
|