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| | NDMC101 Basic information |
| Product Name: | NDMC101 | | Synonyms: | NDMC101;Benzamide, N-(4-chloro-2-fluorophenyl)-2-hydroxy-;NDMC101 >=98% (HPLC);rheumatoid arthritis,inhibit,RAW 264.7,NSAID,Bone,Inhibitor,Nuclear factor-κB,NF-κB,DPP,NDMC101,bone destruction,osteoblast,marrow-derived macrophages,NDMC-101,NDMC 101,synovial inflammation,Nuclear factor-kappaB,Dipeptidyl Peptidase;N-(4-Chloro-2-Fluorophenyl)-2-Hydroxybenzamide | | CAS: | 1308631-40-4 | | MF: | C13H9ClFNO2 | | MW: | 265.67 | | EINECS: | | | Product Categories: | | | Mol File: | 1308631-40-4.mol |  |
| | NDMC101 Chemical Properties |
| Boiling point | 311.1±42.0 °C(Predicted) | | density | 1.452±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml | | form | A crystalline solid | | pka | 8.15±0.30(Predicted) | | color | White to off-white |
| | NDMC101 Usage And Synthesis |
| Uses | NDMC101 is a novel inhibitor of dipeptidyl peptidase-IV activity in human T cells, exhibiting immunomodulatory effects. NDMC101 is also a inhibitor of NFATc1 and NF-κB activity, which play a role in osteoclast differentiation. |
| | NDMC101 Preparation Products And Raw materials |
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