Luotonin F

Luotonin F Suppliers list
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:Luotonin F
CAS:244616-85-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Products Intro: Product Name:Luotonin F
CAS:244616-85-1
Purity:98% Package:25mg; 10mg; 5mg Remarks:Medbio
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:Luotonin F Exclusive
CAS:244616-85-1
Purity:98% Package:1mg;5mg;10mg
Company Name: ApexBio Technology  
Tel: + 1-832-696-8203
Email: sales@apexbt.com
Products Intro: Product Name:Luotonin F
CAS:244616-85-1
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Email: cayman@caymanchem.com
Products Intro: Product Name:Luotonin F
CAS:244616-85-1
Luotonin F Basic information
Product Name:Luotonin F
Synonyms:Luotonin F;2-(quinoline-3-carbonyl)-1H-quinazolin-4-one;Luotonin F Exclusive;4(3H)-Quinazolinone, 2-(3-quinolinylcarbonyl)-;2-(3-quinolinylcarbonyl)-4(3H)-quinazolinone
CAS:244616-85-1
MF:C18H11N3O2
MW:301.3
EINECS:
Product Categories:
Mol File:244616-85-1.mol
Luotonin F Structure
Luotonin F Chemical Properties
Boiling point 542.0±42.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≤2.5mg/ml in DMSO;2.5mg/ml in dimethyl formamide
form crystalline solid
pka2.06±0.11(Predicted)
Safety Information
MSDS Information
Luotonin F Usage And Synthesis
Biological Activityluotonin f is an alkaloid found in the aerial parts of the peganum nigellastrum bunge, a plant which has been long used in traditional chinese medicine for the treatment of rheumatism, abscesses, and various other inflammatory conditions [1].due to their biological and pharmaceutical activities, many synthetic methods have been developed for the synthesis of luotonins. an efficient one-pot synthetic protocol has been proposed for the synthesis of luntonin f from easily available starting materials. through the rational logical design, multifundamental reactions were assembled in one-pot, such as iodination, kornblum oxidation, and annulations [2]. the developed approach could efficiently synthesize luntonin f and various analogues. luotonin f showed promising cytotoxicity against leukemia p-388 cells with an ic50 value of 2.3 μg/ml by stabilizing the dna topoisomerase i-dna complex [1].
references[1] liang j l, cha h c, jahng y. recent advances in the studies on luotonins[j]. molecules, 2011, 16(6): 4861-4883.
[2] zhu y, fei z, liu m, et al. direct one-pot synthesis of luotonin f and analogues via rational logical design[j]. organic letters, 2012, 15(2): 378-381.
Luotonin F Preparation Products And Raw materials
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