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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:Luotonin F
CAS:244616-85-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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MedBioPharmaceutical Technology Inc
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Product Name:Luotonin F
CAS:244616-85-1
Purity:98% Package:25mg; 10mg; 5mg Remarks:Medbio
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
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Product Name:Luotonin F Exclusive
CAS:244616-85-1
Purity:98% Package:1mg;5mg;10mg
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ApexBio Technology
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+ 1-832-696-8203 |
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Product Name:Luotonin F
CAS:244616-85-1
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Cayman Chemical Company
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(800) 364-9897 |
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Product Name:Luotonin F
CAS:244616-85-1
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| | Luotonin F Basic information |
| Product Name: | Luotonin F | | Synonyms: | Luotonin F;2-(quinoline-3-carbonyl)-1H-quinazolin-4-one;Luotonin F Exclusive;4(3H)-Quinazolinone, 2-(3-quinolinylcarbonyl)-;2-(3-quinolinylcarbonyl)-4(3H)-quinazolinone | | CAS: | 244616-85-1 | | MF: | C18H11N3O2 | | MW: | 301.3 | | EINECS: | | | Product Categories: | | | Mol File: | 244616-85-1.mol |  |
| | Luotonin F Chemical Properties |
| Boiling point | 542.0±42.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≤2.5mg/ml in DMSO;2.5mg/ml in dimethyl formamide | | form | crystalline solid | | pka | 2.06±0.11(Predicted) |
| | Luotonin F Usage And Synthesis |
| Biological Activity | luotonin f is an alkaloid found in the aerial parts of the peganum nigellastrum bunge, a plant which has been long used in traditional chinese medicine for the treatment of rheumatism, abscesses, and various other inflammatory conditions [1].due to their biological and pharmaceutical activities, many synthetic methods have been developed for the synthesis of luotonins. an efficient one-pot synthetic protocol has been proposed for the synthesis of luntonin f from easily available starting materials. through the rational logical design, multifundamental reactions were assembled in one-pot, such as iodination, kornblum oxidation, and annulations [2]. the developed approach could efficiently synthesize luntonin f and various analogues. luotonin f showed promising cytotoxicity against leukemia p-388 cells with an ic50 value of 2.3 μg/ml by stabilizing the dna topoisomerase i-dna complex [1]. | | references | [1] liang j l, cha h c, jahng y. recent advances in the studies on luotonins[j]. molecules, 2011, 16(6): 4861-4883.
[2] zhu y, fei z, liu m, et al. direct one-pot synthesis of luotonin f and analogues via rational logical design[j]. organic letters, 2012, 15(2): 378-381. |
| | Luotonin F Preparation Products And Raw materials |
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