Hydronidone
| 中文名称 | Hydronidone |
|---|---|
| 中文同义词 | 化合物 T12732L;棘皮菌素;雷扎芬净(醋酸瑞扎芬净);醋酸瑞扎芬净;棘皮菌素醋酸盐;BIAFUNGIN ACETATE|||SP-3025 ACETATE|||CD101 ACETATE |
| 英文名称 | Hydronidone |
| 英文同义词 | Hydronidone;Biafungin acetate;CD101 acetate;Rezafungin acetate;SP-3025 acetate;Rezafungin (Biafungin) |
| CAS号 | 1631754-41-0 |
| 分子式 | C65H88N8O19 |
| 分子量 | 1285.46 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1631754-41-0.mol |
| 结构式 |  |
Hydronidone 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
Rezafungin (Biafungin) 是下一代，广谱且持久的棘皮菌素。Rezafungin acetate 显示对念珠菌，曲霉和肺孢子菌具有有效的抗真菌活性。
Rezafungin acetate (Biafungin acetate) (1 mg/kg; i.p. once daily for 6 days) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model.
| Animal Model: | C3H/HeN mice |
| Dosage: | 1 mg/kg |
| Administration: | Intraperitoneal injection; once daily for 6 days |
| Result: | Significantly reduced nuclei and asci burdens. |