| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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| Tel: |
18149758185 18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:KRA-533，Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]-
CAS:10161-87-2
Purity:98% Package:1g;10g;100g
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Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]- manufacturers
- KRA-533
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- $134.00 / 2mg
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2024-10-24
- CAS:10161-87-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]- Basic information |
| | Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]- Chemical Properties |
| Boiling point | 530.4±45.0 °C(Predicted) | | density | 1.428±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 2mg/mL, clear | | form | Solid | | pka | 4.34±0.10(Predicted) | | color | White to off-white |
| | Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]- Usage And Synthesis |
| Biological Activity | KRA-333 is a potent and selective KRAS agonist th at binds directly to the GTP/GDP binding pocket of KRAS preventing the cleavage of GTP into GDP and caucusing accumulation of activated GTP-KRAS and suppression of cell growth. KRA-333 promotes apoptosis and autophagic cell death of cancer cells and inhibits growth of mutant KRAS lung cancer in xenografts mice model. |
| | Benzoic acid,4-[4-[(2-bromoacetyl)amino]butyl]- Preparation Products And Raw materials |
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